Megiddo was important in the ancient world. It guarded the western branch of a narrow pass on the most important trade route of the ancient Fertile Crescent, linking Egypt with Mesopotamia and Asia Minor and known today as Via Maris. Because of its strategic location, Megiddo was the site of several battles. It was inhabited approximately from 6500 to 600 BCE,[8] or even since around 7000 BCE,[9] though the first significant remains date to the Chalcolithic period (4500–3500 BCE).